Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
The military parade in Beijing on Sept. 3 that commemorated the 70th anniversary of the end of World War II was the news event that users looked up the most on Baidu's search platform. The celebration featured thousands of troops marching past President Xi Jinping and his predecessors, Hu Jintao and Jiang Zemin, as well as foreign leaders, including President Vladimir V. Putin of Russia.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Co-ops and Condos
WASHINGTON (MarketWatch) — The U.S. economy finally got a big jolt of energy in 2014 after the lamest recovery since World War II. And 2015 is shaping up to be an even better year.
Trends and targets in antiviral phototherapy
The IOM says fewer than 35,000 migrants, or about three percent, have crossed by land into Greece and Bulgaria from Turkey.
Businesses can benefit in other ways too. Craig Rollason, business analysis manager at National Grid, says he has improved his coaching skills by mentoring a Teach Firster.
But with Jrue Holiday back and Anthony Davis putting up historic numbers, they aren't going to be bad enough to get a Fultz or Jackson. Why couldn't last year's draft class be this good?
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
While regulators in the US fret that the pace of growth in the exchange traded fund market may be too explosive, their counterparts in Asia along with asset managers and distributors sweat over what more can be done to raise investor interest.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
In other words, investors are paying far more for Tesla’s future promises than today’s performance by other luxury car manufacturers. Daimler, the manufacturer of Mercedes-Benz, sold more than 2.5 million vehicles last year and has a market cap of about $85 billion. So, although it sells 70 times more vehicles than Tesla, its market cap is less than three times greater.
The Sixers are still slowly pivoting from a full-on institutional tank job to trying to be competitive, and the Suns are not expecting to be anything like good. So those two teams are quasi-tanking. They are, at least, not mad about losing.
ACE2 as a potential therapeutic target for pandemic COVID-19
While many young children try and avoid school work at all costs, the star professes to be a keen student because she wants to avoid the trap of becoming 'a stupid dancer.'
Will the AT&T/Time Warner merger go through without big remedies (such as the sale of CNN)
Diagnostic technologies for COVID-19: a review
China is now home to over 80,000 trade markets and total retail sales of consumer goods would reach 30 trillion yuan this year with consumption contributing to about 60 percent of total GDP growth, Gao said.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Back in the movie wasteland of last January, no one could have guessed what a bounty of good films the year would bring. Not just good films, but several that measure up to our idealized notions of what the medium once was. Two candidates for the top of the heap pretty much chose themselves. For sheer entertainment, the clear call is 'American Hustle,' David O. Russell's joyous celebration of 1970s-era con artists and their intricate cons. For innovation-a new theatrical experience born of new technology-'Gravity' whirls in its own orbit. With the understanding that there's nothing to be said against 'American Hustle,' and everything to recommend this screwball comedy for the ages, I think 'Gravity' is the best movie of the year.
“只要总体市场仍然相对积极，只要交易继续执行良好，我们继续预期今年余下时间会保持健康的交易量，”高盛(Goldman Sachs)美洲股票资本市场主管戴维?路德维格(David Ludwig)表示。
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
“This is a historic moment for Puerto Rico,” said 50-year-old Jose Davila as he waved a large flag from Rossello’s pro-statehood party. “He’s the hope of our island, he’s the hope for statehood, he’s the hope for a people that have suffered.”
Topped with golden leaves and flavored with champagne, the confection was sold for $100 a pop.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
o Battery power may turn out to be a transition technology. Cost reductions have been slow in coming, and Tesla needs a 30% improvement in order to build the $35,000 Model 3 it has promised for 2017. Toyota’s recent move was eye-opening. It is allowing a battery-supply deal with Tesla to expire and instead will redouble its work on hydrogen fuel cells. The cost of fuel cells is coming down faster than batteries and fuel cell proponents believe drivers will prefer a relatively rapid refuel with hydrogen to waiting hours to recharge their batteries.
With the momentum now back behind the iPhone and anticipation growing for the Watch, Mr Cook seems to have won back the confidence of Apple employees, something that analysts say was obvious in his demeanour at this year’s product launches.
Against: Opening so early in the year outside of awards season could hinder its chances.
Influenza neuraminidase: A druggable target for natural products
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.
此次涵盖95个项目（去年为90个）的排行榜中，来自7个国家的9所院校为首次进入榜单。排名第41位的法兰克福金融管理学院(Frankfurt School of Finance & Management)是今年排名最高的新入榜者。这家德国学院拥有性别比例最平衡的项目之一，女性占学员总数的49%。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
3.Video Editing: 19.2 percent increase
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Why does beauty exist? To answer this question, Richard O. Prum, an ornithologist, is working to revive an idea advanced by Charles Darwin: the attractiveness of an animal to another of its species isn’t only tied to fitness and good genes. Rather, animals — especially birds in Dr. Prum’s work — are making subjective decisions. He hopes that evolutionary biologists will stop “explaining away desire.”
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
According to the National Business Daily, the 16 listed banks plan to return 356.2 billion yuan to shareholders as cash dividends in 2015, a decrease of 8.3 billion yuan from the previous year.
Inhibition of SARS coronavirus helicase by bismuth complexes
英国剑桥大学(University of Cambridge)佳奇商学院(Judge Business School)的排名上升5个位次，至第5位。这不仅是该学院首次跻身前5名，而且还是伦敦商学院在这个榜单上首次失去英国最佳商学院这个头衔。
As for bitcoin in the mainstream banking system? “We are still a good year away, in our estimation, from where you can imagine a known financial services company using this,” Ludwin says. “But it’s not 10 years. And when it happens, people will be surprised by how quickly it spreads.”
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
We will speed up the reform of SOEs and state capital.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
By 2020, annual box office sales are expected to reach 100 billion yuan, according to industry estimates.
The cities of Hefei and Xiamen once again led the pack with growth of 48.6 per cent and 45.9 per cent, respectively.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
And the best gig for 2015? That would be an actuary, the people who specialize in financial risk.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
8. Amazon’s Self-Publishing Tools
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
While Jaws's story is extremely unrealistic, it was based on a real series of deaths attributed to a single shark in 1916. In what has been dubbed the "most unique set of shark attacks that ever have occurred," the Jersey Shore saw four people die from shark bites over the course of two weeks. The offending shark was reportedly caught with body parts still in its digestive tract, although leading scientists still aren't sure what drove it to attack so many people.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
NBS senior statistician Sheng Guoqing attributed the slowdown mainly due to a 1.4-percent decline in food prices, which were down for the first time in 15 years.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
“LBS has broadened my profession horizons and opened international career opportunities,” said one graduate. He added: “In the three years after graduation I have worked in the US, Canada and Hong Kong, while rotating in different businesses from corporate banking to debt capitalmarkets”.
From 'heelgate' to the Palm Dog to the 'Dad bod' – it's been a dizzying 12 days. Here are nine lessons from the film festival as it draws to a close.
Remembering the World’s Oldest Person, in the Objects She Left Behind
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
The pair stand on opposite sides backstage and memorize the winners to avoid having to write them down and have revealed in the past how they carry out rigorous checks to ensure they have stuffed the envelopes correctly. It is believed Ruiz and Cullinan are ordered to destroy the duplicate cards as the presentation goes on, so by the time Best Picture is awarded, the only envelopes left are the two for Best Picture.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
For Maddie Ziegler, from Pennsylvania, life couldn't be more different.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
8. How to dip dye hair
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
She is home-tutored alongside her younger sister Mackenzie, who also stars in the Dance Moms series and with whom Maddie released a fashion line called The Maddie & Mackenzie Collection last year.
Lufax, which started four years ago has emerged as the leader due to innovative credit rating techniques.
But a quick look at the changing skyline betrays a frustrating reality: Those shiny new towers have failed to deliver the type of housing most New Yorkers can afford. “There is a disconnect between what we’re building and what we need to build,” said Jonathan J. Miller, the president of the appraisal firm Miller Samuel. “2015 is going to be more of that.”
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
When Finnish programmer Jerry Jalava had a motorcycle accident in 2008, he faced a double tragedy. First, he lost his finger, an obvious problem for anyone who types for a living. Second, he had to deal with a medical team who thought they were comedians—learning of his profession, one surgeon joked that Jalava should go out and buy a “USB finger drive.”
But retail sales growth softened to 10 per cent in October, betraying economists’ expectations it would hold steady at 10.7 per cent growth from September.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
After IMD in second place, Duke Corporate Education completes the custom programme podium. It is the third year in a row that the US school is in third place, having previously topped this ranking for a record 12 consecutive years to 2014.
In a closely fought debate about the six shortlisted titles, one judge described Mr Ford’s book as “a hard-headed and all-encompassing” analysis of the problem. Lionel Barber, FT editor and chair of the judging panel, called The Rise of the Robots “a tightly written and deeply researched addition to the public policy debate”.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
4.You Don't Like Most of Your Coworkers
8. A lovely flower doesn’t belong to the one who appreciates it, but to the dunghill it grows on. (“To stick a lovely flower in the dunghill” is a popular Chinese saying, normally used to describe the common social phenomenon of a pretty girl marrying an ugly but rich guy).
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
But shipments to other destinations fared far worse, particularly those to re-exporter Hong Kong, which saw the dollar value of exports from China contract 26.3 per cent year on year to $33.84bn. Shipments to EU countries also fell 4.7 per cent to $33.5bn, while those to Japan dropped 5.5 per cent to $11.27bn.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Dua Lipa, 'Dua Lipa'
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Among 36,000 who have reached celebrity status on the Internet, 74 percent are women and 87.8 percent are between 17 to 33 years old, while 89 percent have a college education. Followers are also getting younger and better educated, with 77.8 percent in the 17-to-33 age group and 75 percent with a higher education.
In Belgium's case, the reasons are more readily apparent. A nation sewn largely from a patchwork of three peoples, the Flemish, Walloons, and Germans, its football team nevertheless features several stars of African descent. Currently, Belgians of Moroccan descent -- including midfielder Marouane Fellaini and winger Nacer Chadli -- make up the biggest non-European group; for many Moroccans, French is a second language. Like France with its North African and Caribbean contingents and Germany with its Turks, Belgium's national team has benefited from multiple populations: one from Western Europe, one from Africa, and one from Eastern Europe.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Plans to open 20,000 specialist football schools in 2017, aimed at training young players and cultivating talent, are part of the government's latest plan to advance China's ability to compete on the global pitch.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Box office sales in the world's second largest film market have posted average growth of 35 percent year on year since 2003. In 2015 alone, it grew a whopping 48.7 percent, according to the State Administration of Press, Publication, Radio, Film and Television (SARFT).
From the beginning, social networks have been effectively walled off from the Internet. The treasure trove of content on Facebook, for instance, doesn't generally show up on Google (GOOG). But does it have to be that way? Wouldn't it be convenient to see Twitter search results automatically displayed alongside a standard Google search, for example? And why, for instance, don't the latest tweets about a restaurant pop up when you're searching Yelp (YELP)? The competing interests of different networks sends this content behind proprietary walls, but a number of tools offer creative ways to bridge the gulf. (Full disclosure: My company has developed one such tool.)
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
"Students are not suited for starting businesses on their own," said Zhang, adding that vocational students are more eager to start businesses than university undergraduates.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
活跃的ETF市场将取决于基于收费的分销网络的发展。富达国际(Fidelity International)亚太区董事总经理陶博宏(Mark Talbot)表示，分销基础设施正抑制零售需求。
In the field of the best 85 business schools in Europe, HEC Paris remains in second place behind LBS, while Insead, the international school based in Fontainebleau, France, climbs two places to third.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
New artist: Florida Georgia Line
Rankings for Greece, Italy, Portugal and Spain fell dramatically because of the impact of the eurozone crisis, while Egypt, Myanmar and Saudi Arabia registered large falls in the wake of recent political and civil turmoil.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
For: The Los Angeles Critics Association gave it their top prize.
●"Pope Francis Shocks World, Endorses Donald Trump for President, Releases Statement"
Length-scale dependence of protein hydration-shell density
He did several makeup tests to get the look that would so dramatically change Mr. Carell. “We were literally creating a new human being,” Mr. Corso said.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
It was Somerset Maugham who said the French Riviera is “a sunny place for shady people” – and looking around at all the 'models' in the hotel lobbies and the men in dark sunglasses who seemed to know them, I knew what he meant. Behind the festival's shiny facade, there is an unseemly side – and beneath the azure waters, a polluted mess. The French diver and environmentalist Laurent Lombard's video of the Cannes seabed strewn with waste and debris went viral before the festival began. We were assured there was no danger to swimmers, and the mayor had it cleaned up according to the Daily Mail – but the Med had certainly lost some of its sparkle.
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