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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.
虽然周六欧锦赛中爱尔兰0-3不敌比利时,但这并没有让赴波尔多看球的爱尔兰球迷一蹶不振。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 上市房企“白银时代”谋转型
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

The military parade in Beijing on Sept. 3 that commemorated the 70th anniversary of the end of World War II was the news event that users looked up the most on Baidu's search platform. The celebration featured thousands of troops marching past President Xi Jinping and his predecessors, Hu Jintao and Jiang Zemin, as well as foreign leaders, including President Vladimir V. Putin of Russia.
201011/117323.shtml

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 深圳房屋租赁新问题亟需新对策
Open Access Perspective

Soft matter science and the COVID-19 pandemic

● “奥巴马总统证实,如果特朗普当选他将拒绝离开白宫”

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 租赁市场年尾如何“度淡”?
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

《深红报》称,此次被取消入学资格的学生所在的私人脸书群组名为“哈佛饥渴猥琐资产阶级少年”。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Co-ops and Condos
assured
WASHINGTON (MarketWatch) — The U.S. economy finally got a big jolt of energy in 2014 after the lamest recovery since World War II. And 2015 is shaping up to be an even better year.
10.谎言和誓言的区别在于,一个是听的人当真了,一个是说的人当真了。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

The IOM says fewer than 35,000 migrants, or about three percent, have crossed by land into Greece and Bulgaria from Turkey.
Businesses can benefit in other ways too. Craig Rollason, business analysis manager at National Grid, says he has improved his coaching skills by mentoring a Teach Firster.
中国保险企业2016年上半年利润出现大幅下滑。
But with Jrue Holiday back and Anthony Davis putting up historic numbers, they aren't going to be bad enough to get a Fultz or Jackson. Why couldn't last year's draft class be this good?

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

While regulators in the US fret that the pace of growth in the exchange traded fund market may be too explosive, their counterparts in Asia along with asset managers and distributors sweat over what more can be done to raise investor interest.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

报告称,打造“机遇之城”的关键是技术创新和均衡发展。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

In other words, investors are paying far more for Tesla’s future promises than today’s performance by other luxury car manufacturers. Daimler, the manufacturer of Mercedes-Benz, sold more than 2.5 million vehicles last year and has a market cap of about $85 billion. So, although it sells 70 times more vehicles than Tesla, its market cap is less than three times greater.
The Sixers are still slowly pivoting from a full-on institutional tank job to trying to be competitive, and the Suns are not expecting to be anything like good. So those two teams are quasi-tanking. They are, at least, not mad about losing.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

While many young children try and avoid school work at all costs, the star professes to be a keen student because she wants to avoid the trap of becoming 'a stupid dancer.'
Will the AT&T/Time Warner merger go through without big remedies (such as the sale of CNN)

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

China is now home to over 80,000 trade markets and total retail sales of consumer goods would reach 30 trillion yuan this year with consumption contributing to about 60 percent of total GDP growth, Gao said.
15. WeTransfer

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

没戏。这家受到热捧的美国电动车制造商曾经承诺在2018年生产40万辆新款Model 3s。该公司最新的产量目标暗示20万-30万辆。但是电池生产中出现的严重问题意味着一开始就慢了,而且特斯拉的记录不佳。对尚未证明自己离了华尔街不断输入的资金也能活的特斯拉而言,2018年可能会是不成功便成仁的一年。
Back in the movie wasteland of last January, no one could have guessed what a bounty of good films the year would bring. Not just good films, but several that measure up to our idealized notions of what the medium once was. Two candidates for the top of the heap pretty much chose themselves. For sheer entertainment, the clear call is 'American Hustle,' David O. Russell's joyous celebration of 1970s-era con artists and their intricate cons. For innovation-a new theatrical experience born of new technology-'Gravity' whirls in its own orbit. With the understanding that there's nothing to be said against 'American Hustle,' and everything to recommend this screwball comedy for the ages, I think 'Gravity' is the best movie of the year.
“只要总体市场仍然相对积极,只要交易继续执行良好,我们继续预期今年余下时间会保持健康的交易量,”高盛(Goldman Sachs)美洲股票资本市场主管戴维?路德维格(David Ludwig)表示。
我喜欢这个列表(很棒的观点),但是我觉得我要更详细的完善一下怎样成为一个高效老板或者经理。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

trade贸易,mark记号:商标

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

“This is a historic moment for Puerto Rico,” said 50-year-old Jose Davila as he waved a large flag from Rossello’s pro-statehood party. “He’s the hope of our island, he’s the hope for statehood, he’s the hope for a people that have suffered.”
Topped with golden leaves and flavored with champagne, the confection was sold for $100 a pop.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

我预计真正的大戏将在2018年初展开。但这是唐纳德?特朗普的贸易世界。我们只有观看的份儿。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

多数天主教徒(60%)和非福音派白人新教徒(65%)表示,他们相信飓风和洪灾等自然灾害是气候变化所致。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

o Battery power may turn out to be a transition technology. Cost reductions have been slow in coming, and Tesla needs a 30% improvement in order to build the $35,000 Model 3 it has promised for 2017. Toyota’s recent move was eye-opening. It is allowing a battery-supply deal with Tesla to expire and instead will redouble its work on hydrogen fuel cells. The cost of fuel cells is coming down faster than batteries and fuel cell proponents believe drivers will prefer a relatively rapid refuel with hydrogen to waiting hours to recharge their batteries.
一位伦敦软件神童的“硅谷梦”成真,雅虎(Yahoo)斥资近3000万美元收购了他制作的新闻应用。
With the momentum now back behind the iPhone and anticipation growing for the Watch, Mr Cook seems to have won back the confidence of Apple employees, something that analysts say was obvious in his demeanour at this year’s product launches.
Against: Opening so early in the year outside of awards season could hinder its chances.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

4.Autonomous Cars
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.
此次涵盖95个项目(去年为90个)的排行榜中,来自7个国家的9所院校为首次进入榜单。排名第41位的法兰克福金融管理学院(Frankfurt School of Finance & Management)是今年排名最高的新入榜者。这家德国学院拥有性别比例最平衡的项目之一,女性占学员总数的49%。
Bangkok's back!
肺的一项意外功能被发现了。研究人员发现肺不仅仅能促进呼吸作用,在造血方面也起关键作用,肺每小时能制造1000多万血小板(微小的血细胞),这相当于任何特定时刻循环中的血小板的大多数。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

根据中国海关的数据,10月铁矿石进口量较上月环比下降12.3%,同比下降4.9%,而煤炭进口环比下降21.4%,同比下降30.7%。
我国近日发行的2016年猴票同样由黄永玉创作。面值为每张1.2元钱,也颇受关注。在正式发布之前,收集者已经在邮局外排起了长队。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

目前我在创业领域中所关注的大趋势之一是“接触或获得的权利”。创新者们正在将曾经昂贵的、耗时的,或是不可能获得或效率极低的产品带给消费者。无论是学习新技能、激发新兴趣,亦或是叩开此前成本高昂的市场,创业家们正在寻找全新的方式来将独一无二且术业专攻的产品带向更为主流的市场。我们开始看到合作消费商业模式中出现了这个趋势,而我预测,我们将在未来几年看到“基于接触或获得的权利”商业模式的潮涌。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

3.Video Editing: 19.2 percent increase

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Why does beauty exist? To answer this question, Richard O. Prum, an ornithologist, is working to revive an idea advanced by Charles Darwin: the attractiveness of an animal to another of its species isn’t only tied to fitness and good genes. Rather, animals — especially birds in Dr. Prum’s work — are making subjective decisions. He hopes that evolutionary biologists will stop “explaining away desire.”
以美元计算的话,这一跌幅就更加明显了,上个月出口同比下滑11.2%至1774.8亿美元。这一跌幅不仅超过了去年12月1.4%的跌幅,也超过了下滑1.8%的预期。这是自去年3月下滑15%以来的最大跌幅。
该调查发现,211和985重点建设高校毕业生的薪酬水平大幅度领先普通高校毕业生。
消费者的感觉变好。由于就业市场、楼市和股市状况的改善,消费者信心达到四年来的最高水平。美国陷入衰退后,美国人缩减债务,避免借钱并推迟购买。这意味着消费者需求增强的条件可能已经具备,进而可能促使停止招聘的企业开始扩员。信安环球投资有限公司的鲍尔说,企业可能尽可能地提高生产力增长,他表示雇主将需要增员来满足更强劲的需求。qh]

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

门票很快销售一空,只是大多却不是落到铁杆球迷的手中。
com共同,bat打,击-共同打-战斗com bat:共同生活的bat蝙蝠,免不了要combat
在桑迪飓风登陆新泽西Mantoloking之后的早晨,洪水包围了Mantoloking大桥附件的房屋。
ballroom

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

完成所有的事,甚至更多
According to the National Business Daily, the 16 listed banks plan to return 356.2 billion yuan to shareholders as cash dividends in 2015, a decrease of 8.3 billion yuan from the previous year.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

英国剑桥大学(University of Cambridge)佳奇商学院(Judge Business School)的排名上升5个位次,至第5位。这不仅是该学院首次跻身前5名,而且还是伦敦商学院在这个榜单上首次失去英国最佳商学院这个头衔。
As for bitcoin in the mainstream banking system? “We are still a good year away, in our estimation, from where you can imagine a known financial services company using this,” Ludwin says. “But it’s not 10 years. And when it happens, people will be surprised by how quickly it spreads.”
[s?'k?m]
[f]
在英国《金融时报》的年度调查中,欧元区分析师作出了欧洲央行不会采取进一步行动的预言,尽管德拉吉试图说服市场相信:只要整个单一货币区的通胀和经济增长继续令人失望,欧洲央行就将随时准备采取行动。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

We will speed up the reform of SOEs and state capital.
新版《蜘蛛侠》是迄今为止最棒的一部,这主要是因为它很搞笑。这部电影就像是《早餐俱乐部》、《春天不是读书天》遇上《怪胎与书呆》式的幽默。
成长的故事:现代的巴黎郊区与20世纪70年代的旧金山,这两部影片以残酷的城市和无尽的热情,把成长为女人的可怕惊险之路变得戏剧化。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

By 2020, annual box office sales are expected to reach 100 billion yuan, according to industry estimates.
The cities of Hefei and Xiamen once again led the pack with growth of 48.6 per cent and 45.9 per cent, respectively.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 京城最大自住房项目 完成交付
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

别了,《广告狂人》(Mad Men)。别了,那些追踪每集情节(更重要的是,每集服装)的博客和粉丝网站。
拉动你的行李箱,带上你的耐心。假日航空旅行季节即将到来,如果你想有趟轻松愉快的旅程,那么对美国人最好的建议就是选择飞往西部。
And the best gig for 2015? That would be an actuary, the people who specialize in financial risk.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

这个家庭中心内部有三个摄像头,它能够连接到你的手机,你可以通过手机看冰箱里有什么。所以它基本上是一个6000美元替代用纸笔完成购物清单的替代品。
谷歌地图产品经理Bryan Cheng表示,iPhone和Android版用户均可使用该功能。只需打开手机上的谷歌地图,点击屏幕底部的"探索附近饮食",谷歌地图就会根据你所在的地点和时间,分享附近的食物和饮料店铺的地址列表,从"最棒的早餐"到"河畔餐饮"都涵盖在内。
8. Amazon’s Self-Publishing Tools

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

While Jaws's story is extremely unrealistic, it was based on a real series of deaths attributed to a single shark in 1916. In what has been dubbed the "most unique set of shark attacks that ever have occurred," the Jersey Shore saw four people die from shark bites over the course of two weeks. The offending shark was reportedly caught with body parts still in its digestive tract, although leading scientists still aren't sure what drove it to attack so many people.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

NBS senior statistician Sheng Guoqing attributed the slowdown mainly due to a 1.4-percent decline in food prices, which were down for the first time in 15 years.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

课程安排:伊利诺州埃文斯顿校区授课时间为每隔一周的周五至周日;佛罗里达州迈阿密校区每月上一次课,授课时间为周四下午至周日中午
这表明,一般而言,大学教育从长期看来收益良多。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

“LBS has broadened my profession horizons and opened international career opportunities,” said one graduate. He added: “In the three years after graduation I have worked in the US, Canada and Hong Kong, while rotating in different businesses from corporate banking to debt capitalmarkets”.
From 'heelgate' to the Palm Dog to the 'Dad bod' – it's been a dizzying 12 days. Here are nine lessons from the film festival as it draws to a close.
迄今为止,Bigcommerce同名技术的吸引力就在于其简单性,以及与商户同步成长的能力。史蒂夫o凯斯说,“对于一些人来说,成败即系于此。”凯斯以公司董事的身份为Bigcommerce提供美国创业趋势方面的建议。“就在五年前,如果要打造一家有吸引力的网店,你需要花费几十万美元。如今,几个小时就可以搞定,每月成本还不到100美元。”
Remembering the World’s Oldest Person, in the Objects She Left Behind

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

伊莎贝拉卡敏斯卡(Izabella Kaminska)
The pair stand on opposite sides backstage and memorize the winners to avoid having to write them down and have revealed in the past how they carry out rigorous checks to ensure they have stuffed the envelopes correctly. It is believed Ruiz and Cullinan are ordered to destroy the duplicate cards as the presentation goes on, so by the time Best Picture is awarded, the only envelopes left are the two for Best Picture.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

For Maddie Ziegler, from Pennsylvania, life couldn't be more different.
vt. 避免,逃避

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

8. How to dip dye hair

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

She is home-tutored alongside her younger sister Mackenzie, who also stars in the Dance Moms series and with whom Maddie released a fashion line called The Maddie & Mackenzie Collection last year.
Lufax, which started four years ago has emerged as the leader due to innovative credit rating techniques.
But a quick look at the changing skyline betrays a frustrating reality: Those shiny new towers have failed to deliver the type of housing most New Yorkers can afford. “There is a disconnect between what we’re building and what we need to build,” said Jonathan J. Miller, the president of the appraisal firm Miller Samuel. “2015 is going to be more of that.”
(og[coRVqG6sd,

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

When Finnish programmer Jerry Jalava had a motorcycle accident in 2008, he faced a double tragedy. First, he lost his finger, an obvious problem for anyone who types for a living. Second, he had to deal with a medical team who thought they were comedians—learning of his profession, one surgeon joked that Jalava should go out and buy a “USB finger drive.”
But retail sales growth softened to 10 per cent in October, betraying economists’ expectations it would hold steady at 10.7 per cent growth from September.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

中国房价在今年初曾以9.6%的同比增速快速上涨,但此后随着经济放缓以及很多中等规模城市遭遇房产供应过剩,房价一直在下跌。
After IMD in second place, Duke Corporate Education completes the custom programme podium. It is the third year in a row that the US school is in third place, having previously topped this ranking for a record 12 consecutive years to 2014.
In a closely fought debate about the six shortlisted titles, one judge described Mr Ford’s book as “a hard-headed and all-encompassing” analysis of the problem. Lionel Barber, FT editor and chair of the judging panel, called The Rise of the Robots “a tightly written and deeply researched addition to the public policy debate”.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

4.You Don't Like Most of Your Coworkers
8. A lovely flower doesn’t belong to the one who appreciates it, but to the dunghill it grows on. (“To stick a lovely flower in the dunghill” is a popular Chinese saying, normally used to describe the common social phenomenon of a pretty girl marrying an ugly but rich guy).
时间管理类

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

可穿戴设备通常分为三大类:像健身追踪器这样的复杂设备;像智能手表这样的智能配件(由于它们可以运行第三方应用);还有像谷歌眼镜这样完全自主、可以直接联网的智能可穿戴设备。
本田执行副总裁里克o斯考斯特克在一项声明中表示:“我们已经解决了这一问题。本田已经在早期预警报告中采取了一些重大举措来解决过去的缺陷问题,现在我们将更进一步,加强这些举措。我们将继续与国家公路交通安全管理局充分合作,提高透明度,改进报告工作。”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 家装公司进入装修停工期
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

But shipments to other destinations fared far worse, particularly those to re-exporter Hong Kong, which saw the dollar value of exports from China contract 26.3 per cent year on year to $33.84bn. Shipments to EU countries also fell 4.7 per cent to $33.5bn, while those to Japan dropped 5.5 per cent to $11.27bn.
我打赌短期内这些力量——以及美国的首席执行官们——将继续缓和总统在贸易上的火气。不过眼下华盛顿有很多人叫嚣着要在贸易上惩罚中国。
然而,制度也同样重要,因为它们设定了游戏规则。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

[st?k]
Dua Lipa, 'Dua Lipa'

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

这支在11月有着过半胜率的不断进步的球队完全不是垫底球队,这是一支严格意义上的可能的季后赛球队,但是就像所有重建中的球队都会讨论的那样,是靠现有球员和上场时间来换取当下的胜利呢,还是更关注于可持续性的发展呢?
Among 36,000 who have reached celebrity status on the Internet, 74 percent are women and 87.8 percent are between 17 to 33 years old, while 89 percent have a college education. Followers are also getting younger and better educated, with 77.8 percent in the 17-to-33 age group and 75 percent with a higher education.
In Belgium's case, the reasons are more readily apparent. A nation sewn largely from a patchwork of three peoples, the Flemish, Walloons, and Germans, its football team nevertheless features several stars of African descent. Currently, Belgians of Moroccan descent -- including midfielder Marouane Fellaini and winger Nacer Chadli -- make up the biggest non-European group; for many Moroccans, French is a second language. Like France with its North African and Caribbean contingents and Germany with its Turks, Belgium's national team has benefited from multiple populations: one from Western Europe, one from Africa, and one from Eastern Europe.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Plans to open 20,000 specialist football schools in 2017, aimed at training young players and cultivating talent, are part of the government's latest plan to advance China's ability to compete on the global pitch.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

1=somewhat false
90%的学生认为他们大学在创业方面的指导将有助于他们将来的事业。此外,他们还对鼓励创业的政策表示赞赏。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Box office sales in the world's second largest film market have posted average growth of 35 percent year on year since 2003. In 2015 alone, it grew a whopping 48.7 percent, according to the State Administration of Press, Publication, Radio, Film and Television (SARFT).
From the beginning, social networks have been effectively walled off from the Internet. The treasure trove of content on Facebook, for instance, doesn't generally show up on Google (GOOG). But does it have to be that way? Wouldn't it be convenient to see Twitter search results automatically displayed alongside a standard Google search, for example? And why, for instance, don't the latest tweets about a restaurant pop up when you're searching Yelp (YELP)? The competing interests of different networks sends this content behind proprietary walls, but a number of tools offer creative ways to bridge the gulf. (Full disclosure: My company has developed one such tool.)

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 没了安全 遑论安居
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

n. [宗
"Students are not suited for starting businesses on their own," said Zhang, adding that vocational students are more eager to start businesses than university undergraduates.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

diligent
intel在…中间+lig选择,收集+ence→从中选出好的→智力;聪明

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 压减数千亿涉企收费举措细则将出
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

o 特斯拉的规模越大,运营的复杂性就越强。由于它直接销售给终端顾客,免去了特许经销商的环节,它必须开发一个自己的服务中心网络来进行售后维修保养。另外它独特慷慨的保修条款规定,车主在使用三年后,可以以原价50%的价格将车卖还给特斯拉。这种做法可能会催生一个二手特斯拉的专门渠道。“寻找阿尔法”上的一位博主写道:“等到车主觉得他们的车不像一年前那么诱人和罕见,特斯拉可能会吃进大量有三年车龄的二手车。在我看来,这是个潜在的麻烦。”

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

活跃的ETF市场将取决于基于收费的分销网络的发展。富达国际(Fidelity International)亚太区董事总经理陶博宏(Mark Talbot)表示,分销基础设施正抑制零售需求。
8.文盲
In the field of the best 85 business schools in Europe, HEC Paris remains in second place behind LBS, while Insead, the international school based in Fontainebleau, France, climbs two places to third.
2008年,中国政府增加了一个归类为精神疾病的条目:"网瘾症"。据大量官方媒体报道,中国的年轻人花太多时间泡在网吧里,不顾家人和工作玩网络游戏到凌晨,有时甚至不吃,不喝,不睡眠,严重危害了自己的健康。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

不过,人们并没有对周二的峰会寄予过高期望,因为没有任何迹象表明,各国能在政治上实现突破,进而采取更有力的举措。科学家表示,要想如愿把全球变暖控制在各国五年前一致同意的上限,那么未来几年里,就必须扭转排放量上升的势头。现有的所有方案,与实现这一目标都相距甚远。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 城市住房制度长效机制平稳起步
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

New artist: Florida Georgia Line
珍妮·德文表示,“这并不是借口——这是我们经营环境的现实情况。”2012年以来,捷蓝航空公司实施了一系列技术手段,帮助该公司尽快恢复正常,摆脱恶劣天气的影响。她表示,正在使用其他手段来帮助航空公司保证航班准时起降。
Rankings for Greece, Italy, Portugal and Spain fell dramatically because of the impact of the eurozone crisis, while Egypt, Myanmar and Saudi Arabia registered large falls in the wake of recent political and civil turmoil.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

煽动家越是热情洋溢和野心勃勃,民主体制就越有可能沦为专制统治。
戴假牙的角色

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

公告宣称:"我们已经报警,并且收集了证据来维护公司的声誉。而那些泄露裸照的人将被按照法律惩处。"
这张专辑中十分突出的一首歌《Him》(《他》)以低调的方式讲述了一个有关同性恋和文化偏执的催人泪下的故事,是一首倡导非异性恋者公民权的歌曲。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

n. 码,密码,法规,准则

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: “四低”态势仍将被延续
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

For: The Los Angeles Critics Association gave it their top prize.
相比之下,新兴市场出口的平均单价差不多自2012年中以来就一直呈同比下降趋势,2016年2月同比降幅达到16.4%。
●"Pope Francis Shocks World, Endorses Donald Trump for President, Releases Statement"

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

He did several makeup tests to get the look that would so dramatically change Mr. Carell. “We were literally creating a new human being,” Mr. Corso said.
2.你突然变成Twitter上面思想领军人物。
trademark
n. 前进,航行速度,进展,(前后两车间的)车间时距

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

最佳电影奖和最佳导演奖。让人意外的是,诺兰从未获得过奥斯卡奖最佳导演提名。
视频编辑很可能是得益于促进摄影技术工作增长的相同的因素。很显然这一工作的增长是伴随着有经验的吸引人的网站设计的日益增长需求而出现的。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 2020年我国智慧社区将达五成
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

It was Somerset Maugham who said the French Riviera is “a sunny place for shady people” – and looking around at all the 'models' in the hotel lobbies and the men in dark sunglasses who seemed to know them, I knew what he meant. Behind the festival's shiny facade, there is an unseemly side – and beneath the azure waters, a polluted mess. The French diver and environmentalist Laurent Lombard's video of the Cannes seabed strewn with waste and debris went viral before the festival began. We were assured there was no danger to swimmers, and the mayor had it cleaned up according to the Daily Mail – but the Med had certainly lost some of its sparkle.
David Pilling
今年的获奖榜单如下:

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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